Presentation
Rare skin cancers (adnexal carcinomas, inoperable basal cell carcinomas and Merkel cell carcinomas) suffer, at an advanced stage, from a lack of randomised clinical trials and consensus management guidelines, as well as difficulties in accessing innovative diagnostic and therapeutic techniques.
This is why we wish to offer the genomic platform to patients with:
- unresectable or metastatic adnexal carcinomas
- unresectable or metastatic Merkel cell carcinomas following failure of a course of anti-PD-1 or anti-PD-L1 immunotherapy
- unresectable or metastatic basal cell carcinomas following failure of a Sonic Hedgehog pathway inhibitor.
Criteria before considering a discussion in MDM-FMG
- Performance status less than 2
- Estimated life expectancy greater than 3 months
- Indication for systemic treatment, i.e. unresectable or metastatic cancer
- For Merkel cell carcinomas: failure of one line of anti-PD-1 or anti-PD-L1 immunotherapy
- For basal cell carcinomas: failure of a Sonic Hedgehog pathway inhibitor
Genome Sequencing in diagnostic strategy

MDM CARADERM
MDM-FMG Solid tumors adults Curie Paris
MDM coordination team
MDM-FMG Solid tumors adults Gustave Roussy Villejuif
Claudio NICOTRA claudio.nicotra@gustaveroussy.fr
MDM-FMG Solid tumors adults Rennes
Thierry LESIMPLE
Julien EDELINE
Thibault DE LA MOTTE ROUGE
Thierry FEST
Alexandra LESPAGNOL
Florian ESTRADE
MDM-FMG Solid tumors adults Brest
MDM-FMG Solid tumors adults Angers
MDM-FMG Solid tumors adults Nantes
MDM-FMG Solid tumors adults Tours
Arnaud ROMOLI
MDM-FMG Solid tumors adults Caen
MDM-FMG Solid tumors adults Amiens
Bruno CHAUFFERT
Claire POULET
Julie DREMAUX
MDM-FMG Solid tumors adults Lille
MDM-FMG Solid tumors adults Strasbourg
Philippe BARTHELEMY philippe.barthelemy@chru-strasbourg.fr
MDM-FMG Solid tumors adults Nancy
Dr Jean-Marie RAVEL
Dr Laëtitia LAMBERT
Dr Ludovic MANSUY
MDM-FMG Solid tumors adults Dijon
François GHIRINGHELLI
MDM-FMG Solid tumors adults CLB Lyon
Olivier TREDAN olivier.tredan@lyon.unicancer.fr
MDM-FMG Solid tumors adults CITOHL Lyon
Benoît YOU
MDM-FMG Solid tumors adults APHM Marseille
Pascale TOMASINI
MDM-FMG Solid tumors adults IPC Marseille
François BERTUCCI bertuccif@ipc.unicancer.fr
MDM-FMG Solid tumors adults Montpellier
Stanislas QUESADA
MDM-FMG Solid tumors adults Nice
Esma SAADA-BOUZID
MDM-FMG Solid tumors adults Toulouse
MDM-FMG Solid tumors adults Bergonié Bordeaux
Florent PEYRAUD
MDM-FMG Solid tumors adults CHU Bordeaux
Pr Jean-Philippe MERLIO
MDM-FMG Solid tumors adults CHU Poitiers
Camille EVRARD

