Presentation
Familial hemiplegic migraine (FHM) is a rare type of migraine with complex auras, including motor auras, with at least one first- or second-degree relative identified as having the same attacks. FHM is a severe condition: severe migraine episodes (coma, death, irreversible brain damage), possible association with permanent cerebellar ataxia, epilepsy, mental retardation responsible for permanent neurological disability requiring specialised multidisciplinary care.
Criteria before considering a discussion in MDM-FMG
1) Patient presenting with hemiplegic migraine fulfilling to ICHD-3 criteria, confirmed by an expert neurologist or pediatric neurologist.
2) Identification of at least one first- or second-degree relative experiencing similar attacks.
3) The index case and at least one affected relative are available for sampling.
4) Negative first-line diagnostic FHM gene panel testing.
UHTS in diagnostic strategy
MDM cartography
MHF
Paris
Dr Stéphanie GUEY (adult patients, Lariboisière)
Dr Manoëlle KOSSOROTOFF (pediatric patients, Necker)